Is Methyl Octadecatrienoate safe in cosmetics?
Methyl Octadecatrienoate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Octadecatrienoate
Also known as: alpha-Linolenic acid methyl ester, (9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid methyl ester, EINECS 206-102-3, Methyl cis,cis,cis-octadec-9,12,15-trienoate, Methyl alpha-linolenate (+2 more)
INCI: METHYL OCTADECATRIENOATE (CHEMICAL NAME: METHYL LINOLENATE - METHYL ESTER OF Α-LINOLENIC ACID)
Methyl Octadecatrienoate (CAS 301-00-8) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 301-00-8 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, skin conditioning agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
methyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
InChIKey
DVWSXZIHSUZZKJ-YSTUJMKBSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - no specific prohibition; fatty acid methyl esters are generally permitted in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Octadecatrienoate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Regulatory (1)
JECFA Number
346
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Octadecatrienoate.
Regulatory Flags
ifra_fragrance
fda_food_additive
Known Synonyms
alpha-Linolenic acid methyl ester
(9Z,12Z,15Z)-9,12,15-Octadecatrienoic acid methyl ester
EINECS 206-102-3
Methyl cis,cis,cis-octadec-9,12,15-trienoate
Methyl alpha-linolenate
NSC 607759
UNII-0S1NS923K6
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
METHYL LINOLENATE
ChEMBL ID
CHEMBL1172198
Frequently Asked Questions
Is Methyl Octadecatrienoate allowed in the EU?
Methyl Octadecatrienoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Octadecatrienoate do in cosmetics?
Methyl Octadecatrienoate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 301-00-8.
Is Methyl Octadecatrienoate used outside cosmetics?
Methyl Octadecatrienoate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methyl Octadecatrienoate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
Excellent
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
Excellent
Same category
Skin conditioning (emollient)
Acetyl Ornithine
Excellent
Same category
Emollient
Acetyl Proline
Excellent
Same category
Emollient
Acetyl Triethylhexyl Citrate
Excellent
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
Excellent
Same category
Plasticiser, Skin Conditioning (Emoll...
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
Moderate
Similar safety
Skin/hair conditioning (peptide-based...
Lead Acetate
Poor
Chemical family
Historically used as hair darkening a...
OLEAMIDE
Good
Chemical family
Opacifying, Viscosity Controlling
METHACRYLIC ACID/PEG-6 METHACRYLATE/PEG-6 DIMETHACRYLATE CROSSPOLYMER.
Good
Browse nearby
Film Forming
Is Methyl Octadecatrienoate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methyl Octadecatrienoate in your formulation.