Minoxidil Succinoyl Oligopeptide-143

INCI: MINOXIDIL SUCCINOYL OLIGOPEPTIDE-143

CAS Number
Not assigned (novel peptide conjugate)
Function
Hair conditioning / skin conditioning (analogous to other minoxidil-peptide conjugates)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited. Same pharmaceutical grey-zone considerations as other minoxidil derivatives apply.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published safety data; shares concerns with other minoxidil-peptide conjugates regarding potential systemic effects and skin sensitization.. Oligopeptide-143 is a longer-chain peptide conjugate with minoxidil via succinic acid linker; designed for targeted delivery and improved cosmetic efficacy compared to free minoxidil.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Minoxidil Succinoyl Oligopeptide-143 safe in cosmetics?

Limited published safety data; shares concerns with other minoxidil-peptide conjugates regarding potential systemic effects and skin sensitization.. Oligopeptide-143 is a longer-chain peptide conjugate with minoxidil via succinic acid linker; designed for targeted delivery and improved cosmetic efficacy compared to free minoxidil. The EU classifies Minoxidil Succinoyl Oligopeptide-143 as "permitted". Safety rating: MODERATE.

Is Minoxidil Succinoyl Oligopeptide-143 allowed in the EU?

Minoxidil Succinoyl Oligopeptide-143 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Minoxidil Succinoyl Oligopeptide-143 do in cosmetics?

Minoxidil Succinoyl Oligopeptide-143 functions as: Hair conditioning / skin conditioning (analogous to other minoxidil-peptide conjugates). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (novel peptide conjugate).

What is the Margin of Safety for Minoxidil Succinoyl Oligopeptide-143?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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