Mixed Cresols

INCI: MIXED CRESOLS

CAS Number
1319-77-3
Function
Antimicrobial, preservative, antiseptic
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited by FDA, but use is effectively limited. Coal tar-derived cresols carry significant safety restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Highly toxic; corrosive to skin and mucous membranes. Central nervous system depressant. p-Cresol is considered the most hazardous isomer. Canada has prohibited p-cresol and mixtures thereof, while restricting m-cresol and o-cresol individually. A mixture of ortho-, meta-, and para-cresol isomers (methylphenols). Due to systemic toxicity and skin corrosivity, this ingredient has been phased out of cosmetic use globally

โš ๏ธ
Concern Level: High

Regulatory Flags

preservative ifra_fragrance

Frequently Asked Questions

Is Mixed Cresols safe in cosmetics?

Highly toxic; corrosive to skin and mucous membranes. Central nervous system depressant. p-Cresol is considered the most hazardous isomer. Canada has prohibited p-cresol and mixtures thereof, while restricting m-cresol and o-cresol individually. A mixture of ortho-, meta-, and para-cresol isomers (methylphenols). Due to systemic toxicity and skin corrosivity, this ingredient has been phased out of cosmetic use globally The EU classifies Mixed Cresols as "prohibited". Safety rating: MODERATE.

Is Mixed Cresols allowed in the EU?

Mixed Cresols EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Mixed Cresols do in cosmetics?

Mixed Cresols functions as: Antimicrobial, preservative, antiseptic. It is classified as a cosmetic ingredient in our database. CAS number: 1319-77-3.

What is the Margin of Safety for Mixed Cresols?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Mixed Cresols in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Mixed Cresols in your formulation.