Monascus/Angelica Gigas Root Ferment Extract

INCI: MONASCUS/ANGELICA GIGAS ROOT FERMENT EXTRACT

CAS Number
Not individually assigned
Function
Humectant, skin conditioning, emollient
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual concern: citrinin from Monascus fermentation and furanocoumarins/coumarins from Angelica gigas root with potential phototoxicity. Clinical trial data on A. gigas root extracts show efficacy at 50 µg/mL with no reported adverse events, but phototoxicity testing is strongly recommended.

⚠️
Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Monascus/Angelica Gigas Root Ferment Extract safe in cosmetics?

Dual concern: citrinin from Monascus fermentation and furanocoumarins/coumarins from Angelica gigas root with potential phototoxicity. Clinical trial data on A. gigas root extracts show efficacy at 50 µg/mL with no reported adverse events, but phototoxicity testing is strongly recommended. The EU classifies Monascus/Angelica Gigas Root Ferment Extract as "permitted". Safety rating: MODERATE.

Is Monascus/Angelica Gigas Root Ferment Extract allowed in the EU?

Monascus/Angelica Gigas Root Ferment Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Monascus/Angelica Gigas Root Ferment Extract do in cosmetics?

Monascus/Angelica Gigas Root Ferment Extract functions as: Humectant, skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned.

What is the Margin of Safety for Monascus/Angelica Gigas Root Ferment Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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