Is MYRISTALKONIUM CHLORIDE safe in cosmetics?
MYRISTALKONIUM CHLORIDE has a safety rating of "MODERATE" in our database. EU status: restricted. US status: allowed.
Moderate
Cosmetic Ingredient
MYRISTALKONIUM CHLORIDE
Also known as: Benzenemethanaminium, N,N-dimethyl-N-tetradecyl-, chloride, Tetradecyl dimethyl benzyl ammonium chloride, EINECS No.: 205-352-0, ADBAC (C14 100%), Dimethyltetradecylbenzyl ammonium chloride (+14 more)
MYRISTALKONIUM CHLORIDE (CAS 139-08-2) is a cosmetic cosmetic ingredient functioning as Preservative. NOAEL 3.2 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max V/54. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 139-08-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
MYRISTALKONIUM CHLORIDE is classified GHS Danger (H302, H312, H314, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics at max V/54.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Preservative
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
benzyl-dimethyl-tetradecylazanium chloride
InChIKey
OCBHHZMJRVXXQK-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
EU Max Conc.
V/54
US US Status
allowed
US Notes
Allowed — quaternary ammonium compounds are permitted in cosmetics; no specific FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for MYRISTALKONIUM CHLORIDE across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Primary Dermal Irritation, rabbit: Corrosive /ADBAC/ | A skin and eye irritant.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Preservative
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for MYRISTALKONIUM CHLORIDE.
Regulatory Flags
cosing-sourced
eu-restricted
preservative
needs-enrichment
Known Synonyms
Benzenemethanaminium, N,N-dimethyl-N-tetradecyl-, chloride
Tetradecyl dimethyl benzyl ammonium chloride
EINECS No.: 205-352-0
ADBAC (C14 100%)
Dimethyltetradecylbenzyl ammonium chloride
Arquad DM14B-90
Barquat MB 50
Benzyldimethylmyristylammonium chloride
EINECS 205-352-0
Nissan cation M2-100
Quarton 14 BCL
Quaternario 14B
Tetradecyl-dimethyl-benzylammonium chloride
Faringets
Chlorur de miristalkonium
Miristalkonii chloridum
UNII-0W255OL75T
ADBAC (C12 1%, C14 98%, C16 1%)
Alkyl* dimethyl benzyl ammonium chloride *(100% C14)
Chemical Function
Surfactant (surface active agent)
Biocide
Preservative
Regulatory Lists
active_ingredient; detected; Europe; Pesticides
pharmaceutical
active_ingredient; Europe; Pesticides
inert_ingredient; non_food_use; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MIRISTALKONIUM CHLORIDE
ChEMBL ID
CHEMBL421049
Max Phase
2
Frequently Asked Questions
Is MYRISTALKONIUM CHLORIDE allowed in the EU?
MYRISTALKONIUM CHLORIDE EU regulatory status: restricted. Maximum allowed concentration: V/54. This is based on EU Regulation 1223/2009 and its amendments.
What does MYRISTALKONIUM CHLORIDE do in cosmetics?
MYRISTALKONIUM CHLORIDE functions as: Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 139-08-2.
Is MYRISTALKONIUM CHLORIDE used outside cosmetics?
MYRISTALKONIUM CHLORIDE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does MYRISTALKONIUM CHLORIDE have different safety status in cosmetics vs industrial chemicals?
MYRISTALKONIUM CHLORIDE is classified GHS Danger (H302, H312, H314, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics at max V/54.
Compliance Tools
Check MYRISTALKONIUM CHLORIDE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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