Moderate Cosmetic Ingredient NOAEL Data

MYRISTALKONIUM CHLORIDE

CAS Number
139-08-2
Function
Preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Restricted
EU Max Conc. V/54
๐Ÿ‡บ๐Ÿ‡ธ US Status allowed
US Notes Allowed โ€” quaternary ammonium compounds are permitted in cosmetics; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

3 study endpoints found for MYRISTALKONIUM CHLORIDE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL ca.3.2 mg/kg bw/day dermal code:3484 dermal REACH
NOEL 31 mg/kg bw/day oral rat oral REACH
NOEL 31 mg/kg bw/day oral rat oral REACH

Expert Verdict

MYRISTALKONIUM CHLORIDE is listed in the EU CosIng database with functions: Preservative It is restricted under EU Cosmetics Regulation. Restriction: V/54.

โš ๏ธ
Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted preservative needs-enrichment

Frequently Asked Questions

Is MYRISTALKONIUM CHLORIDE safe in cosmetics?

MYRISTALKONIUM CHLORIDE is listed in the EU CosIng database with functions: Preservative It is restricted under EU Cosmetics Regulation. Restriction: V/54. The EU classifies MYRISTALKONIUM CHLORIDE as "Restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is MYRISTALKONIUM CHLORIDE allowed in the EU?

MYRISTALKONIUM CHLORIDE EU regulatory status: Restricted. Maximum allowed concentration: V/54. This is based on EU Regulation 1223/2009 and its amendments.

What does MYRISTALKONIUM CHLORIDE do in cosmetics?

MYRISTALKONIUM CHLORIDE functions as: Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 139-08-2.

What is the NOAEL for MYRISTALKONIUM CHLORIDE?

The NOAEL (No Observed Adverse Effect Level) for MYRISTALKONIUM CHLORIDE is ca.3.2 mg/kg bw/day based on a dermal study via dermal route in code:3484. A total of 3 study endpoints are available. Source: REACH.

๐Ÿ“ฑ

Is MYRISTALKONIUM CHLORIDE in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for MYRISTALKONIUM CHLORIDE in your formulation.