Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for Neomycin based on clinical patch test studies and IFRA standards.
Source: NACDG
Expert Verdict
Neomycin is a potent contact allergen with cross-reactivity to other aminoglycosides, carries ototoxicity and nephrotoxicity risks with systemic absorption, contributes to antimicrobial resistance, and would trigger regulatory reclassification of any cosmetic product containing it. Do not formulate into cosmetics.
Regulatory Flags
Frequently Asked Questions
Is Neomycin safe in cosmetics?
Neomycin is a potent contact allergen with cross-reactivity to other aminoglycosides, carries ototoxicity and nephrotoxicity risks with systemic absorption, contributes to antimicrobial resistance, and would trigger regulatory reclassification of any cosmetic product containing it. Do not formulate into cosmetics. The EU classifies Neomycin as "prohibited". Safety rating: POOR.
Is Neomycin allowed in the EU?
Neomycin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Neomycin do in cosmetics?
Neomycin functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 1404-04-2 (base); 1405-10-3 (sulfate salt).
What is the Margin of Safety for Neomycin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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