Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Amidated variant with no public toxicological dossier; amidation may alter bioactivity compared to free-acid form and comparative safety data is unavailable.
Frequently Asked Questions
Is Nonapeptide-42 Amide safe in cosmetics?
Amidated variant with no public toxicological dossier; amidation may alter bioactivity compared to free-acid form and comparative safety data is unavailable. The EU classifies Nonapeptide-42 Amide as "permitted". Safety rating: MODERATE.
Is Nonapeptide-42 Amide allowed in the EU?
Nonapeptide-42 Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Nonapeptide-42 Amide do in cosmetics?
Nonapeptide-42 Amide functions as: Skin conditioning (predicted based on peptide class). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.
What is the Margin of Safety for Nonapeptide-42 Amide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Nonapeptide-42 Amide compliance across multiple jurisdictions:
Related Ingredients
Is Nonapeptide-42 Amide in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Nonapeptide-42 Amide in your formulation.