Good Cosmetic Ingredient NOAEL Data

OCTYL ACETATE

CAS Number
112-14-1
Function
Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status allowed
US Notes Allowed โ€” GRAS (Generally Recognized As Safe) for food/flavor use; the RIFM completed an updated safety assessment in 2024 confirming safety for fragrance use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

4 study endpoints found for OCTYL ACETATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 500 mg/kg bw/day oral rat oral REACH
NOAEL 100 other oral rat oral REACH

Expert Verdict

OCTYL ACETATE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment epa_safer_alternative ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is OCTYL ACETATE safe in cosmetics?

OCTYL ACETATE is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies OCTYL ACETATE as "Permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is OCTYL ACETATE allowed in the EU?

OCTYL ACETATE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does OCTYL ACETATE do in cosmetics?

OCTYL ACETATE functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 112-14-1.

What is the NOAEL for OCTYL ACETATE?

The NOAEL (No Observed Adverse Effect Level) for OCTYL ACETATE is 500 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 4 study endpoints are available. Source: COSMOS_DB.

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