Oligopeptide-172

INCI: OLIGOPEPTIDE-172

CAS Number
Not publicly assigned
Function
Skin conditioning (synthetic peptide, 73 amino acids — alanine, arginine, asparagine, aspartic acid, glutamic acid, glycine, histidine + others)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically reviewed by FDA or CIR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

At 73 amino acids, this synthetic peptide approaches small protein territory (~8 kDa estimated), potentially increasing immune recognition risk compared to short-chain peptides and warranting immunogenicity assessment for CPSR.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Oligopeptide-172 safe in cosmetics?

At 73 amino acids, this synthetic peptide approaches small protein territory (~8 kDa estimated), potentially increasing immune recognition risk compared to short-chain peptides and warranting immunogenicity assessment for CPSR. The EU classifies Oligopeptide-172 as "permitted". Safety rating: MODERATE.

Is Oligopeptide-172 allowed in the EU?

Oligopeptide-172 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Oligopeptide-172 do in cosmetics?

Oligopeptide-172 functions as: Skin conditioning (synthetic peptide, 73 amino acids — alanine, arginine, asparagine, aspartic acid, glutamic acid, glycine, histidine + others). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for Oligopeptide-172?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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