Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for p-Anisic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 20 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 20 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
High-performing botanical preservative with a clean safety profile. Effective against Gram-negative bacteria at pH below 5.5, making it ideal for acidic formulations. Possesses antioxidant and anti-inflammatory activity. Requires alcohol or complementary co-preservative for complete Gram-positive bacterial coverage. Excellent for pH-controlled, clean-label formulations.
Regulatory Flags
Frequently Asked Questions
Is p-Anisic Acid safe in cosmetics?
High-performing botanical preservative with a clean safety profile. Effective against Gram-negative bacteria at pH below 5.5, making it ideal for acidic formulations. Possesses antioxidant and anti-inflammatory activity. Requires alcohol or complementary co-preservative for complete Gram-positive bacterial coverage. Excellent for pH-controlled, clean-label formulations. The EU classifies p-Anisic Acid as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.
Is p-Anisic Acid allowed in the EU?
p-Anisic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does p-Anisic Acid do in cosmetics?
p-Anisic Acid functions as: preservative, antioxidant, anti-inflammatory. It is classified as a Preservative in our database. CAS number: 100-09-4.
What is the Margin of Safety for p-Anisic Acid?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for p-Anisic Acid?
The NOAEL (No Observed Adverse Effect Level) for p-Anisic Acid is 20 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
Check p-Anisic Acid compliance across multiple jurisdictions:
Related Ingredients
Is p-Anisic Acid in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for p-Anisic Acid in your formulation.