Palmitoyl Tryptamine

INCI: PALMITOYL TRYPTAMINE

CAS Number
Not publicly assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not FDA-restricted; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Tryptamine parent structure is a neuroactive amine with 5-HT receptor affinity; palmitoyl conjugation likely prevents systemic absorption, but supplier toxicology package including dermal penetration, HRIPT, and in vitro genotoxicity data required for CPSR compliance.

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Concern Level: Moderate

Frequently Asked Questions

Is Palmitoyl Tryptamine safe in cosmetics?

Tryptamine parent structure is a neuroactive amine with 5-HT receptor affinity; palmitoyl conjugation likely prevents systemic absorption, but supplier toxicology package including dermal penetration, HRIPT, and in vitro genotoxicity data required for CPSR compliance. The EU classifies Palmitoyl Tryptamine as "permitted". Safety rating: MODERATE.

Is Palmitoyl Tryptamine allowed in the EU?

Palmitoyl Tryptamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Palmitoyl Tryptamine do in cosmetics?

Palmitoyl Tryptamine functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for Palmitoyl Tryptamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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