Is PANCREATIN safe in cosmetics?
PANCREATIN has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
PANCREATIN
PANCREATIN (CAS 8049-47-6) is a cosmetic cosmetic ingredient functioning as Hair Conditioning, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 8049-47-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
PANCREATIN is classified GHS Danger (H315, H317, H319, H334, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair Conditioning, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-benzylsulfonyl-1-morpholin-4-ylethanone
InChIKey
KQGYUJZLKGSELN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| GCC | halal_prohibited | - | All cosmetics |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for PANCREATIN.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
hair-conditioning
needs-enrichment
fda_food_additive
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
active_ingredient; animal_products; Europe; pharmaceutical; residue
Europe; pharmaceutical
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
PANCREATIN
Food Category
food_additive
Frequently Asked Questions
Is PANCREATIN allowed in the EU?
PANCREATIN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PANCREATIN do in cosmetics?
PANCREATIN functions as: Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 8049-47-6.
Is PANCREATIN used outside cosmetics?
PANCREATIN also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does PANCREATIN have different safety status in cosmetics vs industrial chemicals?
PANCREATIN is classified GHS Danger (H315, H317, H319, H334, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check PANCREATIN compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Good
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
MILK
Good
Chemical family
Skin Conditioning
Melanin
Good
Chemical family
Humectant; Softener and conditioner
PANAX GINSENG CALLUS/ADVENTITIOUS ROOT CELL
Good
Browse nearby
Hair Conditioning, Skin Conditioning
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