Poor Cosmetic Ingredient

PEG-10 Diglycidyl Ether

INCI: PEG-10 DIGLYCIDYL ETHER

CAS Number
72207-80-8 (generic for PEG diglycidyl ethers)
Function
Crosslinking agent (primarily industrial, not a standard cosmetic-use ingredient)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No CIR review; not recognized as a cosmetic ingredient by CIR or FDA VCRP

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Contains reactive epoxide (oxirane) groups — strong skin sensitizer (H317), skin irritant (H315), serious eye irritant (H319); potential genotoxic/mutagenic concern from epoxide reactivity; NOT appropriate for cosmetic formulation; industrial crosslinker only

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Concern Level: High

Regulatory Flags

potential-allergen peg-ingredient

Frequently Asked Questions

Is PEG-10 Diglycidyl Ether safe in cosmetics?

CRITICAL: Contains reactive epoxide (oxirane) groups — strong skin sensitizer (H317), skin irritant (H315), serious eye irritant (H319); potential genotoxic/mutagenic concern from epoxide reactivity; NOT appropriate for cosmetic formulation; industrial crosslinker only The EU classifies PEG-10 Diglycidyl Ether as "permitted". Safety rating: POOR.

Is PEG-10 Diglycidyl Ether allowed in the EU?

PEG-10 Diglycidyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-10 Diglycidyl Ether do in cosmetics?

PEG-10 Diglycidyl Ether functions as: Crosslinking agent (primarily industrial, not a standard cosmetic-use ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 72207-80-8 (generic for PEG diglycidyl ethers).

What is the Margin of Safety for PEG-10 Diglycidyl Ether?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check PEG-10 Diglycidyl Ether compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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