Pentaerythrityl Hydrogenated Rosinate
INCI: PENTAERYTHRITYL HYDROGENATED ROSINATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Pentaerythrityl Hydrogenated Rosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 3000 ppm | oral | rat | oral | REACH |
| NOEL | 3000 ppm | oral | - | oral | REACH |
| NOAEL | 18000 other | oral | rat | oral | REACH |
| NOAEL | 18000 other | oral | - | oral | REACH |
| NOEL | 500 other | oral | rat | oral | REACH |
| NOEL | 500 other | oral | - | oral | REACH |
| NOEL | 500 other | oral | rat | oral | REACH |
| NOEL | 500 other | oral | - | oral | REACH |
| NOEL | 10000 ppm | oral | rat | oral | REACH |
| NOEL | 10000 ppm | oral | - | oral | REACH |
Expert Verdict
Rosin derivative with colophony-related sensitization potential. CIR found data insufficient for parent compound (pentaerythrityl rosinate). Hydrogenation reduces sensitization vs. unmodified rosin but does not eliminate it. Missing genotoxicity assays, dermal absorption data, and impurity profiles.
Regulatory Flags
Frequently Asked Questions
Is Pentaerythrityl Hydrogenated Rosinate safe in cosmetics?
Rosin derivative with colophony-related sensitization potential. CIR found data insufficient for parent compound (pentaerythrityl rosinate). Hydrogenation reduces sensitization vs. unmodified rosin but does not eliminate it. Missing genotoxicity assays, dermal absorption data, and impurity profiles. The EU classifies Pentaerythrityl Hydrogenated Rosinate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Pentaerythrityl Hydrogenated Rosinate allowed in the EU?
Pentaerythrityl Hydrogenated Rosinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pentaerythrityl Hydrogenated Rosinate do in cosmetics?
Pentaerythrityl Hydrogenated Rosinate functions as: Film forming; viscosity increasing – nonaqueous; skin conditioning – emollient. It is classified as a cosmetic ingredient in our database. CAS number: 64365-17-9.
What is the Margin of Safety for Pentaerythrityl Hydrogenated Rosinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Pentaerythrityl Hydrogenated Rosinate?
The NOAEL (No Observed Adverse Effect Level) for Pentaerythrityl Hydrogenated Rosinate is 3000 ppm based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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