Pentafluoropropane

INCI: PENTAFLUOROPROPANE

CAS Number
460-73-1 (1,1,1,3,3-pentafluoropropane; HFC-245fa)
Function
Propellant, solvent for aerosol cosmetics
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted as aerosol propellant. EPA SNAP-listed as acceptable substitute for CFCs/HCFCs

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted aerosol propellant with environmental concerns: GWP ~858 and subject to EU F-gas phase-down. Inhalation risk if used improperly in enclosed spaces.

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Concern Level: Moderate

Frequently Asked Questions

Is Pentafluoropropane safe in cosmetics?

Permitted aerosol propellant with environmental concerns: GWP ~858 and subject to EU F-gas phase-down. Inhalation risk if used improperly in enclosed spaces. The EU classifies Pentafluoropropane as "permitted". Safety rating: GOOD.

Is Pentafluoropropane allowed in the EU?

Pentafluoropropane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pentafluoropropane do in cosmetics?

Pentafluoropropane functions as: Propellant, solvent for aerosol cosmetics. It is classified as a cosmetic ingredient in our database. CAS number: 460-73-1 (1,1,1,3,3-pentafluoropropane; HFC-245fa).

What is the Margin of Safety for Pentafluoropropane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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