Poor Cosmetic Ingredient GHS Classified

t-Butyl Acetate

INCI: T-BUTYL ACETATE (NOT A STANDARD COSMETIC INCI IN COSING — PRIMARILY AN INDUSTRIAL SOLVENT)

CAS Number
540-88-5
Function
Solvent (industrial); adhesive/sealant chemical; paint additive
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not listed in the FDA VCRP ingredient dictionary for cosmetic use; industrial chemical

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The vapour is irritating to the respiratory tract. The substance is mildly irritating to the eyes and skin. Exposure far above the OEL could cause lowering of consciousness.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour.

Expert Verdict

Not a recognized cosmetic ingredient. Flammable (Flash point ~22°C); CNS depression at high exposure; industrial solvent only — do not formulate into cosmetics without full SCCS-level safety assessment

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Concern Level: High

Frequently Asked Questions

Is t-Butyl Acetate safe in cosmetics?

Not a recognized cosmetic ingredient. Flammable (Flash point ~22°C); CNS depression at high exposure; industrial solvent only — do not formulate into cosmetics without full SCCS-level safety assessment The EU classifies t-Butyl Acetate as "permitted". Safety rating: POOR.

Is t-Butyl Acetate allowed in the EU?

t-Butyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does t-Butyl Acetate do in cosmetics?

t-Butyl Acetate functions as: Solvent (industrial); adhesive/sealant chemical; paint additive. It is classified as a cosmetic ingredient in our database. CAS number: 540-88-5.

What is the Margin of Safety for t-Butyl Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check t-Butyl Acetate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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