Moderate Cosmetic Ingredient GHS Classified

Pentane

INCI: PENTANE

CAS Number
109-66-0
Function
Solvent, Propellant, Viscosity controlling
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted by FDA for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
flam;flame; excl mark;warn; cancer;health haz
Hazard Statements
Highly flammable liquid and vapour May cause drowsiness or dizziness May be fatal if swallowed and enters airways Toxic to aquatic life
Short-term Exposure Effects
If swallowed the substance easily enters the airways and could result in aspiration pneumonitis. Inhalation of high concentrations of the vapour may cause depression of the central nervous system.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.

Expert Verdict

Extremely flammable with flash point of -49ยฐC; CNS depressant at high inhalation concentrations; VOC with regulatory limits in some jurisdictions; must not be used in enclosed or poorly ventilated applications; aerosol products require specific flammability labeling per Regulation 1223/2009 Article 19.

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Concern Level: Moderate

Frequently Asked Questions

Is Pentane safe in cosmetics?

Extremely flammable with flash point of -49ยฐC; CNS depressant at high inhalation concentrations; VOC with regulatory limits in some jurisdictions; must not be used in enclosed or poorly ventilated applications; aerosol products require specific flammability labeling per Regulation 1223/2009 Article 19. The EU classifies Pentane as "restricted". Safety rating: MODERATE.

Is Pentane allowed in the EU?

Pentane EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pentane do in cosmetics?

Pentane functions as: Solvent, Propellant, Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 109-66-0.

What is the Margin of Safety for Pentane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Is Pentane classified as hazardous under GHS?

Pentane carries a GHS signal word of "DANGER". Hazard statements: Highly flammable liquid and vapour May cause drowsiness or dizziness May be fatal if swallowed and enters airways Toxic to aquatic life. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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