Moderate Cosmetic Ingredient GHS Classified

Pentanone

INCI: PENTANONE

CAS Number
107-87-9
Function
Solvent, Denaturant
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FEMA GRAS as flavoring; not specifically restricted by FDA in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. Exposure above the OEL could cause lowering of consciousness.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Expert Verdict

Flammable (flash point ~7 °C); irritant at concentrated levels; CNS effects at high inhalation exposure; keep residual levels low in finished product; not suitable as primary solvent in leave-on formulations

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Concern Level: Moderate

Regulatory Flags

ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Pentanone safe in cosmetics?

Flammable (flash point ~7 °C); irritant at concentrated levels; CNS effects at high inhalation exposure; keep residual levels low in finished product; not suitable as primary solvent in leave-on formulations The EU classifies Pentanone as "permitted". Safety rating: MODERATE.

Is Pentanone allowed in the EU?

Pentanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pentanone do in cosmetics?

Pentanone functions as: Solvent, Denaturant. It is classified as a cosmetic ingredient in our database. CAS number: 107-87-9.

What is the Margin of Safety for Pentanone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Pentanone compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

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Ethyl Perfluorobutyl Ether
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Hexane
Poor
C12-15 Isoparaffin
Good
Cyclohexane
Poor
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