Cyclohexane

INCI: CYCLOHEXANE

CAS Number
110-82-7 (general chemical data; not a standard cosmetic INCI entry)
Function
Industrial solvent; not typically used as an intentional cosmetic ingredient due to volatility and inhalation/central nervous system toxicity.
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes No CIR cosmetic monograph; not recognized as a standard cosmetic ingredient; any use would be as residual solvent with limits established via ICH/Q3C-type reasoning.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strong flammable solvent with CNS depression hazards; not suitable as a cosmetic ingredient, only as a controlled residual impurity.

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Concern Level: High

Regulatory Flags

fda_food_additive jecfa_concern

Frequently Asked Questions

Is Cyclohexane safe in cosmetics?

Strong flammable solvent with CNS depression hazards; not suitable as a cosmetic ingredient, only as a controlled residual impurity. The EU classifies Cyclohexane as "prohibited". Safety rating: POOR.

Is Cyclohexane allowed in the EU?

Cyclohexane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyclohexane do in cosmetics?

Cyclohexane functions as: Industrial solvent; not typically used as an intentional cosmetic ingredient due to volatility and inhalation/central nervous system toxicity.. It is classified as a cosmetic ingredient in our database. CAS number: 110-82-7 (general chemical data; not a standard cosmetic INCI entry).

What is the Margin of Safety for Cyclohexane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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