Phloroglucinol Trimethyl Ether

INCI: PHLOROGLUCINOL TRIMETHYL ETHER

CAS Number
621-23-8 [^1_17]
Function
Fragrance / skin conditioning (1,3,5-trimethoxybenzene)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted as fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very low reported use concentrations with no major safety concerns at current cosmetic-use levels; ensure fragrance allergen compliance if reformulating at higher concentrations.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Phloroglucinol Trimethyl Ether safe in cosmetics?

Very low reported use concentrations with no major safety concerns at current cosmetic-use levels; ensure fragrance allergen compliance if reformulating at higher concentrations. The EU classifies Phloroglucinol Trimethyl Ether as "permitted". Safety rating: GOOD.

Is Phloroglucinol Trimethyl Ether allowed in the EU?

Phloroglucinol Trimethyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phloroglucinol Trimethyl Ether do in cosmetics?

Phloroglucinol Trimethyl Ether functions as: Fragrance / skin conditioning (1,3,5-trimethoxybenzene). It is classified as a cosmetic ingredient in our database. CAS number: 621-23-8 [^1_17].

What is the Margin of Safety for Phloroglucinol Trimethyl Ether?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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