Phosphorothioate DNA-1

INCI: PHOSPHOROTHIOATE DNA-1

CAS Number
Not assigned
Function
Skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific ruling; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel biotech ingredient with extremely limited cosmetic toxicological data; no published NOAEL/LOAEL for dermal route; sulfur-modified backbone requires verification of residual solvents and heavy metals from synthesis; CPSR assessor will likely require additional supporting data.

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Concern Level: Moderate

Frequently Asked Questions

Is Phosphorothioate DNA-1 safe in cosmetics?

Novel biotech ingredient with extremely limited cosmetic toxicological data; no published NOAEL/LOAEL for dermal route; sulfur-modified backbone requires verification of residual solvents and heavy metals from synthesis; CPSR assessor will likely require additional supporting data. The EU classifies Phosphorothioate DNA-1 as "permitted". Safety rating: MODERATE.

Is Phosphorothioate DNA-1 allowed in the EU?

Phosphorothioate DNA-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Phosphorothioate DNA-1 do in cosmetics?

Phosphorothioate DNA-1 functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Phosphorothioate DNA-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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