Moderate Cosmetic Ingredient NOAEL Data

Pigment Yellow 13

INCI: PIGMENT YELLOW 13

CAS Number
5102-83-0
Function
Colorant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not FDA-listed for cosmetic use; unlawful for US cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

5 study endpoints found for Pigment Yellow 13. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 9000 ppm oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 9000 ppm oral rat oral REACH
NOAEL 500 mg/kg bw/day oral rat oral REACH

Expert Verdict

Contains 3,3'-dichlorobenzidine release risk similar to Pigment Yellow 12; prohibited in US cosmetics; purity specifications critical for safe use in permitted jurisdictions.

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Concern Level: Moderate

Regulatory Flags

colorant eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Pigment Yellow 13 safe in cosmetics?

Contains 3,3'-dichlorobenzidine release risk similar to Pigment Yellow 12; prohibited in US cosmetics; purity specifications critical for safe use in permitted jurisdictions. The EU classifies Pigment Yellow 13 as "permitted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.

Is Pigment Yellow 13 allowed in the EU?

Pigment Yellow 13 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pigment Yellow 13 do in cosmetics?

Pigment Yellow 13 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 5102-83-0.

What is the Margin of Safety for Pigment Yellow 13?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Pigment Yellow 13?

The NOAEL (No Observed Adverse Effect Level) for Pigment Yellow 13 is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.

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