Piper Retrofractum Fruit Extract
INCI: PIPER RETROFRACTUM FRUIT EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Javanese long pepper contains piperlongumine, which has documented cytotoxic activity in vitro. Insufficient published dermal safety data — CPSR assessor will likely require supplier tox package including acute dermal irritation, sensitisation LLNA, and genotoxicity battery minimum.
Regulatory Flags
Frequently Asked Questions
Is Piper Retrofractum Fruit Extract safe in cosmetics?
Javanese long pepper contains piperlongumine, which has documented cytotoxic activity in vitro. Insufficient published dermal safety data — CPSR assessor will likely require supplier tox package including acute dermal irritation, sensitisation LLNA, and genotoxicity battery minimum. The EU classifies Piper Retrofractum Fruit Extract as "permitted". Safety rating: MODERATE.
Is Piper Retrofractum Fruit Extract allowed in the EU?
Piper Retrofractum Fruit Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Piper Retrofractum Fruit Extract do in cosmetics?
Piper Retrofractum Fruit Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not listed in CosIng.
What is the Margin of Safety for Piper Retrofractum Fruit Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Piper Retrofractum Fruit Extract compliance across multiple jurisdictions:
Related Ingredients
Is Piper Retrofractum Fruit Extract in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Piper Retrofractum Fruit Extract in your formulation.