Piperazine Bisferulate

INCI: PIPERAZINE BISFERULATE

CAS Number
96585-18-1
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed by FDA; general cosmetic ingredient status

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Piperazine backbone presents dermal and respiratory sensitization potential per Health Canada and EU assessments; safety assessment must confirm bis-ferulate ester does not hydrolyze to free piperazine on skin; no SCCS opinion or CIR review available.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Piperazine Bisferulate safe in cosmetics?

Piperazine backbone presents dermal and respiratory sensitization potential per Health Canada and EU assessments; safety assessment must confirm bis-ferulate ester does not hydrolyze to free piperazine on skin; no SCCS opinion or CIR review available. The EU classifies Piperazine Bisferulate as "permitted". Safety rating: MODERATE.

Is Piperazine Bisferulate allowed in the EU?

Piperazine Bisferulate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piperazine Bisferulate do in cosmetics?

Piperazine Bisferulate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 96585-18-1.

What is the Margin of Safety for Piperazine Bisferulate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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