Piperlonguminine

INCI: PIPERLONGUMININE

CAS Number
5950-12-9
Function
Skin conditioning; anti-inflammatory alkaloid amide
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed by FDA for cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Conjugated unsaturated amide system could theoretically act as a weak Michael acceptor with no SCCS opinion, CIR review, or established use history in finished cosmetic products.

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Concern Level: Moderate

Frequently Asked Questions

Is Piperlonguminine safe in cosmetics?

Conjugated unsaturated amide system could theoretically act as a weak Michael acceptor with no SCCS opinion, CIR review, or established use history in finished cosmetic products. The EU classifies Piperlonguminine as "permitted". Safety rating: MODERATE.

Is Piperlonguminine allowed in the EU?

Piperlonguminine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piperlonguminine do in cosmetics?

Piperlonguminine functions as: Skin conditioning; anti-inflammatory alkaloid amide. It is classified as a cosmetic ingredient in our database. CAS number: 5950-12-9.

What is the Margin of Safety for Piperlonguminine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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