Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Piperonyl Acetone. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 66.1 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 66.1 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Fragrance ingredient subject to IFRA guidelines; label as PARFUM.
Regulatory Flags
Frequently Asked Questions
Is Piperonyl Acetone safe in cosmetics?
Fragrance ingredient subject to IFRA guidelines; label as PARFUM. The EU classifies Piperonyl Acetone as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Piperonyl Acetone allowed in the EU?
Piperonyl Acetone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Piperonyl Acetone do in cosmetics?
Piperonyl Acetone functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 55418-52-5.
What is the Margin of Safety for Piperonyl Acetone?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Piperonyl Acetone?
The NOAEL (No Observed Adverse Effect Level) for Piperonyl Acetone is 66.1 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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