Is Poloxamer 188 Succinate safe in cosmetics?
Poloxamer 188 Succinate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Poloxamer 188 Succinate
INCI: POLOXAMER 188 SUCCINATE
Poloxamer 188 Succinate (CAS Not assigned) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not assigned →
Function
Skin conditioning agent
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not independently CIR-reviewed; derivative of CIR-assessed Poloxamer 188
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Poloxamer 188 Succinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Poloxamer 188 Succinate — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Poloxamer 188 Succinate allowed in the EU?
Poloxamer 188 Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamer 188 Succinate do in cosmetics?
Poloxamer 188 Succinate functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
Compliance Tools
Check Poloxamer 188 Succinate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
EXCELLENT
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
EXCELLENT
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
EXCELLENT
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
EXCELLENT
Same category
Skin Conditioning
Acetylneuraminic Acid
EXCELLENT
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
EXCELLENT
Same category
Skin Conditioning, Hair Conditioning;...
(20S)-Protopanaxadiol
MODERATE
Similar safety
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
MODERATE
Similar safety
Antimicrobial, antioxidant, humectant
(Licorice/Reynoutria Japonica) Root/Stem Extract
MODERATE
Similar safety
Skin conditioning, antioxidant
(SH-Pentapeptide-10 6-Aminocaprooyl SH-Pentapeptide-11) SP
MODERATE
Similar safety
Skin/hair conditioning (peptide-based...
1,2,3,4,4a,5,6,7-Octahydro-2,5,5-Trimethyl-2-Naphthol
MODERATE
Similar safety
Fragrance ingredient
1,2,3,4,4a,7,8,8a-Octahydro-2,4a,5,8a-Tetramethyl-Naphthyl Formate
MODERATE
Similar safety
Fragrance ingredient
POLY 1,2-BUTANEDIOL-6 PROPYLENE GLYCOL
GOOD
Browse nearby
Solvent
POLY METHYL STYRENE ISOPROPANOL KETONE
GOOD
Browse nearby
Light Stabilizer
POLY(1-4 BUTANEDIOL)-27
GOOD
Browse nearby
Not Reported
Is Poloxamer 188 Succinate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Poloxamer 188 Succinate in your formulation.