Poloxamine 1304

INCI: POLOXAMINE 1304

CAS Number
11111-34-5
Function
Surfactant – Cleansing; Surfactant – Emulsifying
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA monograph; no CIR assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Poloxamine 1304 is a surfactant with potential 1,4-dioxane and ethylene oxide/propylene oxide residuals; lacks dedicated safety monograph.

⚠️
Concern Level: Moderate

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Poloxamine 1304 safe in cosmetics?

Poloxamine 1304 is a surfactant with potential 1,4-dioxane and ethylene oxide/propylene oxide residuals; lacks dedicated safety monograph. The EU classifies Poloxamine 1304 as "permitted". Safety rating: MODERATE.

Is Poloxamine 1304 allowed in the EU?

Poloxamine 1304 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 1304 do in cosmetics?

Poloxamine 1304 functions as: Surfactant – Cleansing; Surfactant – Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 1304?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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