Poloxamine 701

INCI: POLOXAMINE 701

CAS Number
11111-34-5
Function
Surfactant – emulsifying, dispersant, demulsifier, antifoaming agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

H317 skin sensitization classification; very low HLB with predominantly lipophilic character resulting in higher dermal interaction risk than high-EO grades.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen ifra_fragrance

Frequently Asked Questions

Is Poloxamine 701 safe in cosmetics?

H317 skin sensitization classification; very low HLB with predominantly lipophilic character resulting in higher dermal interaction risk than high-EO grades. The EU classifies Poloxamine 701 as "permitted". Safety rating: MODERATE.

Is Poloxamine 701 allowed in the EU?

Poloxamine 701 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 701 do in cosmetics?

Poloxamine 701 functions as: Surfactant – emulsifying, dispersant, demulsifier, antifoaming agent. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 701?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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