Poloxamine 901

INCI: POLOXAMINE 901

CAS Number
11111-34-5
Function
Surfactant – emulsifying, dispersant, demulsifier, antifoaming agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very low HLB — high lipophilicity increases dermal interaction potential; same structural concerns as 701

⚠️
Concern Level: Moderate

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Poloxamine 901 safe in cosmetics?

Very low HLB — high lipophilicity increases dermal interaction potential; same structural concerns as 701 The EU classifies Poloxamine 901 as "permitted". Safety rating: MODERATE.

Is Poloxamine 901 allowed in the EU?

Poloxamine 901 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamine 901 do in cosmetics?

Poloxamine 901 functions as: Surfactant – emulsifying, dispersant, demulsifier, antifoaming agent. It is classified as a cosmetic ingredient in our database. CAS number: 11111-34-5.

What is the Margin of Safety for Poloxamine 901?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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