Poor Cosmetic Ingredient

Poly(1,4-Butanediol)-11

INCI: POLY(1,4-BUTANEDIOL)-11

CAS Number
Not assigned
Function
Reference INCI name (may not be a marketed cosmetic ingredient)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not CIR-reviewed; CIR found insufficient data for 1,4-Butanediol monomer

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: 1,4-Butanediol is a known prodrug for GHB (gamma-hydroxybutyrate); CIR explicitly found insufficient data to determine safety for 1,4-Butanediol; monomer residuals are a serious concern; this may be a reference INCI only, not intended for formulation

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Concern Level: High

Frequently Asked Questions

Is Poly(1,4-Butanediol)-11 safe in cosmetics?

CRITICAL: 1,4-Butanediol is a known prodrug for GHB (gamma-hydroxybutyrate); CIR explicitly found insufficient data to determine safety for 1,4-Butanediol; monomer residuals are a serious concern; this may be a reference INCI only, not intended for formulation The EU classifies Poly(1,4-Butanediol)-11 as "permitted". Safety rating: POOR.

Is Poly(1,4-Butanediol)-11 allowed in the EU?

Poly(1,4-Butanediol)-11 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poly(1,4-Butanediol)-11 do in cosmetics?

Poly(1,4-Butanediol)-11 functions as: Reference INCI name (may not be a marketed cosmetic ingredient). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Poly(1,4-Butanediol)-11?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Poly(1,4-Butanediol)-11 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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