Polygala Senega Root Extract

INCI: POLYGALA SENEGA ROOT EXTRACT

CAS Number
68990-66-9 / 90082-95-4
Function
Refreshing; skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific CIR review; historical use in traditional medicine; permitted under general cosmetic safety provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains senegin saponins with potential irritant activity at high concentrations; hemolytic activity of saponins documented at systemic exposure (not relevant at typical cosmetic use levels); botanical source must be standardized and tested for contaminants

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Polygala Senega Root Extract safe in cosmetics?

Contains senegin saponins with potential irritant activity at high concentrations; hemolytic activity of saponins documented at systemic exposure (not relevant at typical cosmetic use levels); botanical source must be standardized and tested for contaminants The EU classifies Polygala Senega Root Extract as "permitted". Safety rating: MODERATE.

Is Polygala Senega Root Extract allowed in the EU?

Polygala Senega Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polygala Senega Root Extract do in cosmetics?

Polygala Senega Root Extract functions as: Refreshing; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68990-66-9 / 90082-95-4.

What is the Margin of Safety for Polygala Senega Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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