Polyglyceryl-2 Oleate

INCI: POLYGLYCERYL-2 OLEATE

Polyglyceryl-2 Oleate (CAS 49553-76-6 / 9007-48-1 (generic)) is a cosmetic cosmetic ingredient functioning as Skin-conditioning agent – emollient; surfactant – emulsifying agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 49553-76-6 / 9007-48-1 (generic) →

CAS Number
49553-76-6 / 9007-48-1 (generic)
View industrial chemical safety profile →
Function
Skin-conditioning agent – emollient; surfactant – emulsifying agent
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR: Safe as used (2016/2023); FDA-approved as inactive ingredient in drug products (Polyglyceryl-3 Oleate approved in topical, oral, vaginal drugs)

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-2 Oleate.

Calculate MoS for your specific formulation with the MoS Calculator.

Editorial summary

Preliminary editorial summary for Polyglyceryl-2 Oleate — not a computed safety verdict. See the sourced toxicological data above.

Frequently Asked Questions

Is Polyglyceryl-2 Oleate safe in cosmetics?

Polyglyceryl-2 Oleate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Polyglyceryl-2 Oleate allowed in the EU?

Polyglyceryl-2 Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-2 Oleate do in cosmetics?

Polyglyceryl-2 Oleate functions as: Skin-conditioning agent – emollient; surfactant – emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 49553-76-6 / 9007-48-1 (generic).

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