Polyglyceryl-4 Isostearate

INCI: POLYGLYCERYL-4 ISOSTEARATE

CAS Number
63705-03-3 / 91824-88-3
Function
Skin-conditioning agent – emollient; surfactant – emulsifying agent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; CIR: safe as used (2023)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-documented ingredient with excellent safety profile and adequate margin of safety; safe for use as formulated.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Polyglyceryl-4 Isostearate safe in cosmetics?

Well-documented ingredient with excellent safety profile and adequate margin of safety; safe for use as formulated. The EU classifies Polyglyceryl-4 Isostearate as "permitted". Safety rating: EXCELLENT.

Is Polyglyceryl-4 Isostearate allowed in the EU?

Polyglyceryl-4 Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Polyglyceryl-4 Isostearate do in cosmetics?

Polyglyceryl-4 Isostearate functions as: Skin-conditioning agent – emollient; surfactant – emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 63705-03-3 / 91824-88-3.

What is the Margin of Safety for Polyglyceryl-4 Isostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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