Moderate Cosmetic Ingredient

Potato SH-Polypeptide-11

INCI: POTATO SH-POLYPEPTIDE-11

CAS Number
106096-93-9 (base aFGF/FGF-1 molecule)
Function
Skin conditioning, hair conditioning, fibroblast growth stimulation, collagen and elastin synthesis, wound healing
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No pre-market approval required; not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Acidic Fibroblast Growth Factor (FGF-1) that stimulates fibroblast proliferation and angiogenesis; shares theoretical concerns with other growth factors and should be avoided on compromised or wounded skin in formulated products without clinical data.

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Concern Level: Moderate

Frequently Asked Questions

Is Potato SH-Polypeptide-11 safe in cosmetics?

Acidic Fibroblast Growth Factor (FGF-1) that stimulates fibroblast proliferation and angiogenesis; shares theoretical concerns with other growth factors and should be avoided on compromised or wounded skin in formulated products without clinical data. The EU classifies Potato SH-Polypeptide-11 as "permitted". Safety rating: MODERATE.

Is Potato SH-Polypeptide-11 allowed in the EU?

Potato SH-Polypeptide-11 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potato SH-Polypeptide-11 do in cosmetics?

Potato SH-Polypeptide-11 functions as: Skin conditioning, hair conditioning, fibroblast growth stimulation, collagen and elastin synthesis, wound healing. It is classified as a cosmetic ingredient in our database. CAS number: 106096-93-9 (base aFGF/FGF-1 molecule).

What is the Margin of Safety for Potato SH-Polypeptide-11?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Potato SH-Polypeptide-11 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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