Good Cosmetic Ingredient NOAEL Data

PPG-9 Butyl Ether

INCI: PPG-9 BUTYL ETHER

CAS Number
29894-35-7
Function
Skin conditioning agent; hair conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; CIR reviewed alkyl PEG/PPG ethers class and found safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for PPG-9 Butyl Ether. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 845 mg/kg bw/day oral rat oral REACH
NOAEL 167 2105 1992 rat inhalation REACH
NOAEL >=8000 mg/kg bw/day oral rat oral REACH
NOEL 50000 ppm oral rat oral REACH
LOAEL 5 other oral rat oral REACH
NOAEL 10000 mg/kg bw/day oral rat oral REACH

Expert Verdict

No major concerns; propoxylation residuals (propylene oxide) should be controlled via supplier specifications

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Concern Level: Low

Frequently Asked Questions

Is PPG-9 Butyl Ether safe in cosmetics?

No major concerns; propoxylation residuals (propylene oxide) should be controlled via supplier specifications The EU classifies PPG-9 Butyl Ether as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.

Is PPG-9 Butyl Ether allowed in the EU?

PPG-9 Butyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PPG-9 Butyl Ether do in cosmetics?

PPG-9 Butyl Ether functions as: Skin conditioning agent; hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 29894-35-7.

What is the Margin of Safety for PPG-9 Butyl Ether?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for PPG-9 Butyl Ether?

The NOAEL (No Observed Adverse Effect Level) for PPG-9 Butyl Ether is 845 mg/kg bw/day based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.

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