Primula Denticulata Leaf Extract

INCI: PRIMULA DENTICULATA LEAF EXTRACT

CAS Number
92129-21-0
Function
Skin Conditioning; anti-acne (sebum regulation, pore reduction) per patent literature
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific monograph; patented for topical acne treatment (US Patent 7,381,433). Permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Primula allergen risk: Primin is a well-documented contact sensitizer. Must verify primin content in extract specification. Paula's Choice flags limited data . Requires patch testing protocol for sensitive skin formulations

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Primula Denticulata Leaf Extract safe in cosmetics?

Primula allergen risk: Primin is a well-documented contact sensitizer. Must verify primin content in extract specification. Paula's Choice flags limited data . Requires patch testing protocol for sensitive skin formulations The EU classifies Primula Denticulata Leaf Extract as "permitted". Safety rating: MODERATE.

Is Primula Denticulata Leaf Extract allowed in the EU?

Primula Denticulata Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Primula Denticulata Leaf Extract do in cosmetics?

Primula Denticulata Leaf Extract functions as: Skin Conditioning; anti-acne (sebum regulation, pore reduction) per patent literature. It is classified as a cosmetic ingredient in our database. CAS number: 92129-21-0.

What is the Margin of Safety for Primula Denticulata Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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