Propagermanium

INCI: NOT AN INCI-LISTED COSMETIC INGREDIENT

CAS Number
12758-40-6
Function
Antiviral/immunomodulatory drug (pharmaceutical); organogermanium compound
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not approved for cosmetic use; investigational pharmaceutical

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿ›‘ PHARMACEUTICAL/INVESTIGATIONAL. Organogermanium compounds linked to renal toxicity, neurotoxicity, and hepatotoxicity. Withdrawn from market in Japan. No cosmetic use is justified or permissible.

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Concern Level: High

Frequently Asked Questions

Is Propagermanium safe in cosmetics?

๐Ÿ›‘ PHARMACEUTICAL/INVESTIGATIONAL. Organogermanium compounds linked to renal toxicity, neurotoxicity, and hepatotoxicity. Withdrawn from market in Japan. No cosmetic use is justified or permissible. The EU classifies Propagermanium as "prohibited". Safety rating: POOR.

Is Propagermanium allowed in the EU?

Propagermanium EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Propagermanium do in cosmetics?

Propagermanium functions as: Antiviral/immunomodulatory drug (pharmaceutical); organogermanium compound. It is classified as a cosmetic ingredient in our database. CAS number: 12758-40-6.

What is the Margin of Safety for Propagermanium?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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