Good Cosmetic Ingredient GHS Classified

Propane

Also known as: EINECS 200-827-9, Hydrocarbon Propellant A-108, Petroleum gas, liquefied, Propyldihydride, UNII-T75W9911L6 (+3 more)

INCI: PROPANE

Propane (CAS 74-98-6) is a cosmetic cosmetic ingredient functioning as Propellant (aerosol products). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 74-98-6 →

Auto-generated CPSR Part A draft with source citations
Function
Propellant (aerosol products)
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C3H8
MW
44.1 g/mol
EC Number
200-827-9
PubChem CID
6334
IUPAC Name
propane
InChIKey
ATUOYWHBWRKTHZ-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted as cosmetic ingredient (propellant); also GRAS

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Propane.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the central nervous system.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
FlammableCompressed Gas
Hazard Class and Category
Flam. Gas 1; Press. Gas
Hazard Statements
  • H220 Extremely flammable gas

Inserted via ATP: CLP00

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000,000 - 10,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (2)
ICSC Safety Card
0319
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
At concn up to 10% (100,000 ppm) ... propane caused no noticeable irritation to the eyes, nose, or resp tract.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (2)
JECFA Evaluation
PROPANE | 2015 | NOT SPECIFIED | Not re-evaluated by JECFA, but the provisions for propane was withdrawn at CCFA47 | TRS 648-JECFA 23/23 | NOT PREPARED
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Propellants non-motive (blowing agents)
Regulatory List Membership (2)
EU Restricted for Children (Cosmetics) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Propane.

Regulatory Flags

eu_children_restricted fda_food_additive jecfa_safe

Known Synonyms

EINECS 200-827-9 Hydrocarbon Propellant A-108 Petroleum gas, liquefied Propyldihydride UNII-T75W9911L6 CH3-CH2-CH3 E944 Propan

Chemical Function

Propellants non-motive (blowing agents)

Regulatory Lists

Europe; Vehicle - car interior drinking_water; Europe; manufacturing; plastic_additive inert_ingredient; non_food_use; Pesticides Arts and crafts/Office supplies - general arts and crafts supplies - flocking; Europe Arts and crafts/Office supplies - general arts and crafts supplies; Europe Arts and crafts/Office supplies - general arts and crafts supplies; Europe Cleaning products and household care - shoes; Europe Cleaning products and household care - shoes; Europe consumer_product; Europe consumer_product; detected; Europe active_ingredient; animal_products; Europe; pharmaceutical; residue Europe; Vehicle - car interior air; detected; emissions; Europe; Vehicle - car interior detected; Europe; Vehicle - car interior Cleaning products and household care - oven - oven cleaner; Europe children; Europe; Personal care children; Europe; Personal care Cleaning products and household care; Europe

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
PROPANE
ChEMBL ID
CHEMBL135416
Max Phase
-1
Adverse Event Associations
17
View full pharmaceutical profile →

Frequently Asked Questions

Is Propane safe in cosmetics?

Propane has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Propane allowed in the EU?

Propane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propane do in cosmetics?

Propane functions as: Propellant (aerosol products). It is classified as a cosmetic ingredient in our database. CAS number: 74-98-6.

Is Propane used outside cosmetics?

Propane also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Propane have different safety status in cosmetics vs industrial chemicals?

Propane is classified GHS Danger (H220, H280, H336) in the chemicals database but is allowed in EU cosmetics.

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