Is Propolis Extract safe in cosmetics?
Propolis Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Propolis Extract
INCI: PROPOLIS EXTRACT
Propolis Extract (CAS 85665-41-4) is a cosmetic cosmetic ingredient functioning as Anti-inflammatory via NF-κB inhibition by caffeic acid phenethyl ester (CAPE),. EU Regulation 1223/2009 status: permitted, max 10%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 85665-41-4 →
Function
Anti-inflammatory via NF-κB inhibition by caffeic acid phenethyl ester (CAPE), antimicrobial, antioxidant
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
EU Max Conc.
10%
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Propolis Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (1)
EU Regulated in Personal Care
Editorial summary
Preliminary editorial summary for Propolis Extract — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
Sensitizer
Chemical Function
Softener and conditioner
Humectant
Pharmaceutical
Regulatory Lists
Europe
Personal care
Europe
Personal care
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
1
Frequently Asked Questions
Is Propolis Extract allowed in the EU?
Propolis Extract EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.
What does Propolis Extract do in cosmetics?
Propolis Extract functions as: Anti-inflammatory via NF-κB inhibition by caffeic acid phenethyl ester (CAPE), antimicrobial, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 85665-41-4.
Is Propolis Extract used outside cosmetics?
Propolis Extract also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Propolis Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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