Propylene Glycol Butyl Ether

INCI: PROPYLENE GLYCOL BUTYL ETHER (ALSO KNOWN AS PNB; PPG-1 BUTYL ETHER IN SOME COSMETIC CONTEXTS)

CAS Number
5131-66-8 (primary); 29387-86-8 (alternate)
Function
Solvent; coalescent; coupling agent (primarily industrial); limited cosmetic use as solvent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR Expert Panel reviewed PPG Butyl Ethers as a class โ€” concluded safe in present practices of use when formulated to be nonirritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

โš  Glycol ether class โ€” some glycol ethers have reproductive toxicity concerns (though PnB specifically has low reproductive risk per OECD). โš  Residual propylene oxide may be present from manufacture

โš ๏ธ
Concern Level: High

Frequently Asked Questions

Is Propylene Glycol Butyl Ether safe in cosmetics?

โš  Glycol ether class โ€” some glycol ethers have reproductive toxicity concerns (though PnB specifically has low reproductive risk per OECD). โš  Residual propylene oxide may be present from manufacture The EU classifies Propylene Glycol Butyl Ether as "permitted". Safety rating: MODERATE.

Is Propylene Glycol Butyl Ether allowed in the EU?

Propylene Glycol Butyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Butyl Ether do in cosmetics?

Propylene Glycol Butyl Ether functions as: Solvent; coalescent; coupling agent (primarily industrial); limited cosmetic use as solvent. It is classified as a cosmetic ingredient in our database. CAS number: 5131-66-8 (primary); 29387-86-8 (alternate).

What is the Margin of Safety for Propylene Glycol Butyl Ether?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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