Propylene Glycol Laurate

INCI: PROPYLENE GLYCOL LAURATE

CAS Number
142-55-2 / 27194-74-7 / 37321-62-3 / 199282-83-2
Function
Skin-conditioning agent (emollient); Surfactant (emulsifying agent)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; CIR: safe as used (1999, reaffirmed 2014); PG mono/diesters GRAS for food; active VCRP uses

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Four CAS numbers (different manufacturers/isomeric forms); known penetration enhancer for certain drugs; "slightly irritating" in rabbit study โ€“ formulate to be non-irritating per CIR requirement

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Concern Level: Moderate

Frequently Asked Questions

Is Propylene Glycol Laurate safe in cosmetics?

Four CAS numbers (different manufacturers/isomeric forms); known penetration enhancer for certain drugs; "slightly irritating" in rabbit study โ€“ formulate to be non-irritating per CIR requirement The EU classifies Propylene Glycol Laurate as "permitted". Safety rating: GOOD.

Is Propylene Glycol Laurate allowed in the EU?

Propylene Glycol Laurate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Propylene Glycol Laurate do in cosmetics?

Propylene Glycol Laurate functions as: Skin-conditioning agent (emollient); Surfactant (emulsifying agent). It is classified as a cosmetic ingredient in our database. CAS number: 142-55-2 / 27194-74-7 / 37321-62-3 / 199282-83-2.

What is the Margin of Safety for Propylene Glycol Laurate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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