2,4-Hexadienal

INCI: 2,4-HEXADIENAL (ALSO KNOWN AS SORBALDEHYDE)

CAS Number
142-83-6 (trans,trans-isomer, most common)
Function
Fragrance
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted as fragrance ingredient; FEMA GRAS for food flavoring

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

α,β-γ,δ-unsaturated aldehyde - high structural alert for protein binding and skin sensitization; must verify IFRA use limits; mutagenic potential flagged in some QSAR models

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Concern Level: High

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is 2,4-Hexadienal safe in cosmetics?

α,β-γ,δ-unsaturated aldehyde - high structural alert for protein binding and skin sensitization; must verify IFRA use limits; mutagenic potential flagged in some QSAR models The EU classifies 2,4-Hexadienal as "permitted". Safety rating: MODERATE.

Is 2,4-Hexadienal allowed in the EU?

2,4-Hexadienal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,4-Hexadienal do in cosmetics?

2,4-Hexadienal functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 142-83-6 (trans,trans-isomer, most common).

What is the Margin of Safety for 2,4-Hexadienal?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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