Regulatory Status
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Safety Data
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Expert Verdict
Acetamide MEA (CAS 142-26-7) is permitted in both EU and US. EU permits with no annex restriction but nitrosamine formation risk requires formulation controls. US CIR determined safe for rinse-off products and leave-on formulations at concentrations ≤7.5%; nitrosating co-ingredients must be avoided. Acetamide parent compound is IARC Group 2B at high chronic doses, not applicable to MEA derivative in cosmetic use.
Regulatory Flags
Frequently Asked Questions
Is Acetamide MEA safe in cosmetics?
Acetamide MEA (CAS 142-26-7) is permitted in both EU and US. EU permits with no annex restriction but nitrosamine formation risk requires formulation controls. US CIR determined safe for rinse-off products and leave-on formulations at concentrations ≤7.5%; nitrosating co-ingredients must be avoided. Acetamide parent compound is IARC Group 2B at high chronic doses, not applicable to MEA derivative in cosmetic use. The EU classifies Acetamide MEA as "permitted". Safety rating: MODERATE.
Is Acetamide MEA allowed in the EU?
Acetamide MEA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetamide MEA do in cosmetics?
Acetamide MEA functions as: Humectant; hair and skin conditioning agent. It is classified as a Humectant in our database. CAS number: 142-26-7.
What is the Margin of Safety for Acetamide MEA?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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