Pyrus Malus Callus Powder

INCI: PYRUS MALUS CALLUS POWDER [^1_17]

CAS Number
Not specifically assigned (parent CAS 85251-63-4 for Pyrus malus derivatives)
Function
Skin Conditioning [^1_17]
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted but CIR 2016 found data INSUFFICIENT for the related Malus Domestica (Apple) Callus Extract [^1_1]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR 2016 explicitly concluded data INSUFFICIENT for apple callus ingredients [^1_1]; plant cell culture-derived โ€” composition depends heavily on culture medium, growth conditions, and processing; COSMILE Europe database incorrectly lists plant origin as "Annatto Shrub" (data entry error โ€” actual source is apple) [^1_17]; request full supplier safety dossier including characterization, stability, and toxicological data before formulation

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Concern Level: High

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Pyrus Malus Callus Powder safe in cosmetics?

CIR 2016 explicitly concluded data INSUFFICIENT for apple callus ingredients [^1_1]; plant cell culture-derived โ€” composition depends heavily on culture medium, growth conditions, and processing; COSMILE Europe database incorrectly lists plant origin as "Annatto Shrub" (data entry error โ€” actual source is apple) [^1_17]; request full supplier safety dossier including characterization, stability, and toxicological data before formulation The EU classifies Pyrus Malus Callus Powder as "permitted". Safety rating: MODERATE.

Is Pyrus Malus Callus Powder allowed in the EU?

Pyrus Malus Callus Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyrus Malus Callus Powder do in cosmetics?

Pyrus Malus Callus Powder functions as: Skin Conditioning [^1_17]. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (parent CAS 85251-63-4 for Pyrus malus derivatives).

What is the Margin of Safety for Pyrus Malus Callus Powder?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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