Quaternium-45

INCI: QUATERNIUM-45

CAS Number
21034-17-3
Function
Antistatic
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; historically also known as Sensitizer/Photosensitizer 401 (photographic chemical crossover)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Unusual chemical structure for a cosmetic quat โ€” verify intended application carefully; iodide-containing; phenylamino moiety raises sensitization questions; very rarely used in modern formulations

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Quaternium-45 safe in cosmetics?

Unusual chemical structure for a cosmetic quat โ€” verify intended application carefully; iodide-containing; phenylamino moiety raises sensitization questions; very rarely used in modern formulations The EU classifies Quaternium-45 as "permitted". Safety rating: MODERATE.

Is Quaternium-45 allowed in the EU?

Quaternium-45 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Quaternium-45 do in cosmetics?

Quaternium-45 functions as: Antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 21034-17-3.

What is the Margin of Safety for Quaternium-45?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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