Rauvolfia Serpentina Root Extract

INCI: RAUVOLFIA SERPENTINA ROOT EXTRACT

CAS Number
90106-13-1
Function
Astringent, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted for topical cosmetic use; however, reserpine is a prescription drug substance โ€” presence in cosmetics could trigger drug classification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿ”ด HIGH RISK: Reserpine is EU Annex II prohibited (entry \#411). Contains pharmacologically active alkaloids. CITES Appendix II listed species โ€” sourcing documentation required. Traditional medicine use (Ayurveda) does NOT validate cosmetic safety. Requires full alkaloid characterization, heavy metal testing, and legal review before use

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Concern Level: High

Regulatory Flags

plant-extract eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Rauvolfia Serpentina Root Extract safe in cosmetics?

๐Ÿ”ด HIGH RISK: Reserpine is EU Annex II prohibited (entry \#411). Contains pharmacologically active alkaloids. CITES Appendix II listed species โ€” sourcing documentation required. Traditional medicine use (Ayurveda) does NOT validate cosmetic safety. Requires full alkaloid characterization, heavy metal testing, and legal review before use The EU classifies Rauvolfia Serpentina Root Extract as "prohibited". Safety rating: MODERATE.

Is Rauvolfia Serpentina Root Extract allowed in the EU?

Rauvolfia Serpentina Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Rauvolfia Serpentina Root Extract do in cosmetics?

Rauvolfia Serpentina Root Extract functions as: Astringent, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90106-13-1.

What is the Margin of Safety for Rauvolfia Serpentina Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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