Retinoyl Tetrapeptide-43 Amide

INCI: RETINOYL TETRAPEPTIDE-43 AMIDE

CAS Number
Not publicly assigned/available
Function
Skin conditioning (anti-aging retinoid-peptide conjugate)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific monograph; permitted as cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

C-terminal amide modification may enhance stability; no independent safety data available

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Concern Level: Moderate

Frequently Asked Questions

Is Retinoyl Tetrapeptide-43 Amide safe in cosmetics?

C-terminal amide modification may enhance stability; no independent safety data available The EU classifies Retinoyl Tetrapeptide-43 Amide as "permitted". Safety rating: MODERATE.

Is Retinoyl Tetrapeptide-43 Amide allowed in the EU?

Retinoyl Tetrapeptide-43 Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Retinoyl Tetrapeptide-43 Amide do in cosmetics?

Retinoyl Tetrapeptide-43 Amide functions as: Skin conditioning (anti-aging retinoid-peptide conjugate). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.

What is the Margin of Safety for Retinoyl Tetrapeptide-43 Amide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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