Regulatory Status
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Safety Data
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Expert Verdict
EU-banned. China also prohibits human oligopeptide-1/EGF in cosmetics . Growth factor activity raises theoretical concerns about uncontrolled cell proliferation. Gene origin is human — the "rh-" prefix is the regulatory trigger.
Frequently Asked Questions
Is Rh-Oligopeptide-1 safe in cosmetics?
EU-banned. China also prohibits human oligopeptide-1/EGF in cosmetics . Growth factor activity raises theoretical concerns about uncontrolled cell proliferation. Gene origin is human — the "rh-" prefix is the regulatory trigger. The EU classifies Rh-Oligopeptide-1 as "prohibited". Safety rating: MODERATE.
Is Rh-Oligopeptide-1 allowed in the EU?
Rh-Oligopeptide-1 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Rh-Oligopeptide-1 do in cosmetics?
Rh-Oligopeptide-1 functions as: Skin conditioning (recombinant human Epidermal Growth Factor — EGF). It is classified as a cosmetic ingredient in our database. CAS number: 62253-63-8 (shared with sh-Oligopeptide-1/EGF variants).
What is the Margin of Safety for Rh-Oligopeptide-1?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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