Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
EU-banned. bFGF is a potent mitogen — promotes fibroblast, endothelial, and smooth muscle cell proliferation. Theoretical concern for angiogenesis stimulation. Pregnancy/breastfeeding data lacking .
Frequently Asked Questions
Is Rh-Polypeptide-1 safe in cosmetics?
EU-banned. bFGF is a potent mitogen — promotes fibroblast, endothelial, and smooth muscle cell proliferation. Theoretical concern for angiogenesis stimulation. Pregnancy/breastfeeding data lacking . The EU classifies Rh-Polypeptide-1 as "prohibited". Safety rating: MODERATE.
Is Rh-Polypeptide-1 allowed in the EU?
Rh-Polypeptide-1 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Rh-Polypeptide-1 do in cosmetics?
Rh-Polypeptide-1 functions as: Skin conditioning, skin protecting (recombinant human Basic Fibroblast Growth Factor — bFGF/FGF-2, up to 210 amino acids). It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.
What is the Margin of Safety for Rh-Polypeptide-1?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Rh-Polypeptide-1 compliance across multiple jurisdictions:
Related Ingredients
Is Rh-Polypeptide-1 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Rh-Polypeptide-1 in your formulation.